Description

5-Hydroxymethyl-1,2-Dihydro-Pyrrolo[3,2,1-Ij]Quinolin-4-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing novel polycyclic frameworks with potential biological activity.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in academic and industrial R&D labs.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of related APIs.

Basic Information

Product Name	5-Hydroxymethyl-1,2-Dihydro-Pyrrolo[3,2,1-Ij]Quinolin-4-One
CAS No.	574740-70-8
Molecular Formula	C14H13NO2
Molecular Weight	227.26 g/mol
Synonyms	5-(Hydroxymethyl)-1,2-dihydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one; 5-Hydroxymethyl-1,2-dihydropyrrolo[3,2,1-ij]quinolin-4(4aH)-one; 1,2-Dihydro-5-(hydroxymethyl)pyrrolo[3,2,1-ij]quinolin-4-one; Pyrroloquinolinone derivative; Fused tricyclic hydroxymethyl ketone
EINECS	Contact for details

Quality Control

Our production of 5-Hydroxymethyl-1,2-Dihydro-Pyrrolo[3,2,1-Ij]Quinolin-4-One adheres to stringent quality management protocols. Each batch is analytically verified using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP-compliant applications in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.