Description

5-Aminoquinoline-8-Carbonitrile is a high-purity, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both an amino and a nitrile group on a quinoline scaffold, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active compounds and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition, anti-malarial, and anti-cancer activities.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the quinoline core's bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of organic semiconductors, luminescent materials, and metal-organic frameworks (MOFs) due to its electron-rich and coordinating properties.
• Dye and Pigment Chemistry: Acts as a building block for synthesizing advanced quinoline-based dyes and functional colorants.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and for exploring new chemical transformations.

Basic Information

Product Name	5-Aminoquinoline-8-Carbonitrile
CAS No.	573758-03-9
Molecular Formula	C10H7N3
Molecular Weight	169.18 g/mol
Synonyms	8-Cyano-5-aminoquinoline; 5-Amino-8-cyanoquinoline; Quinoline-8-carbonitrile, 5-amino-; 5-Aminoquinoline-8-carbonitrile; 5-Amino-8-quinolinecarbonitrile; 573758-03-9; 5-Amino-8-cyanquinoline
EINECS	Contact for details

Quality Control

Our 5-Aminoquinoline-8-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder/crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.