Description

7-Bromo-4-Chloroquinazoline is a high-purity halogenated quinazoline derivative, a crucial advanced pharmaceutical intermediate. Its value lies in its versatile reactivity, particularly as a key building block for constructing complex molecules in medicinal chemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of targeted therapies and kinase inhibitors.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for synthesizing novel drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Chemical Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce diverse functional groups.
• Research & Development (R&D): Essential for medicinal chemists in structure-activity relationship (SAR) studies and lead optimization processes.
• Agrochemical Intermediate: Potential use in the synthesis of advanced crop protection agents and herbicides.
• Material Science Precursor: Can be used in the development of organic electronic materials and ligands for catalysis.

Basic Information

Item	Detail
Product Name	7-Bromo-4-Chloroquinazoline
CAS No.	573675-55-5
Molecular Formula	C8H4BrClN2
Molecular Weight	243.49 g/mol
Synonyms	4-Chloro-7-bromoquinazoline; 7-Bromo-4-chloro-quinazoline; Quinazoline, 7-bromo-4-chloro-; 573675-55-5; 4-Chloro-7-bromo-quinazoline
EINECS	Contact for details

Quality Control

Our 7-Bromo-4-Chloroquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.