Description

(S)-4-Phenyl-3-p-Tolyloxazolidin-2-One is a high-value chiral oxazolidinone derivative, serving as a critical building block in asymmetric synthesis. Its primary value lies in its role as a chiral auxiliary, enabling the stereoselective construction of complex molecules with high enantiomeric purity. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Chiral Auxiliary in Asymmetric Synthesis: Used to control stereochemistry in key bond-forming reactions such as aldol, alkylation, and Diels-Alder reactions.
• Pharmaceutical Intermediate: A crucial precursor in the research and production of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Catalyst and Ligand Development: Serves as a scaffold or precursor for novel chiral catalysts and ligands used in homogeneous catalysis.
• Fine Chemical Synthesis: Employed in the custom synthesis of complex, high-value specialty chemicals for agrochemical and material science applications.
• Academic and R&D Laboratories: A standard reagent for methodological development in organic chemistry and stereochemistry studies.

Basic Information

Product Name	(S)-4-Phenyl-3-p-Tolyloxazolidin-2-One
CAS No.	572923-05-8
Molecular Formula	C16H15NO2
Molecular Weight	253.30 g/mol
Synonyms	(S)-4-Phenyl-3-(4-methylphenyl)-1,3-oxazolidin-2-one; (S)-3-(p-Tolyl)-4-phenyloxazolidin-2-one; (S)-4-Phenyl-3-(p-tolyl)oxazolidin-2-one; (S)-3-(4-Methylphenyl)-4-phenyl-2-oxazolidinone; (S)-p-Tolyl Phenyl Oxazolidinone; (S)-Evans Auxiliary Derivative; (S)-Oxazolidinone Chiral Auxiliary
EINECS	Contact for details

Quality Control

We supply (S)-4-Phenyl-3-p-Tolyloxazolidin-2-One in high-purity grades suitable for demanding synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.