Description

tert-Butyl 8,8-Dimethyl-3-Nitro-7,8-Dihydro-1,6-Naphthyridine-6(5H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 570409-62-0. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its defined stereochemistry and functional groups that enable precise downstream chemical transformations. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing novel molecular libraries in drug discovery programs.
• Process Chemistry Development: Serves as a critical raw material for optimizing scalable and efficient synthetic routes for target molecules.
• Academic & Industrial R&D: Employed in chemical research to study reaction mechanisms and develop new synthetic methodologies.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.

Basic Information

Product Name	tert-Butyl 8,8-Dimethyl-3-Nitro-7,8-Dihydro-1,6-Naphthyridine-6(5H)-Carboxylate
CAS No.	570409-62-0
Molecular Formula	C15H21N3O4
Molecular Weight	307.35 g/mol
Synonyms	8,8-Dimethyl-3-nitro-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylic acid tert-butyl ester; tert-Butyl 8,8-dimethyl-3-nitro-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carboxylate; 6-tert-Butoxycarbonyl-8,8-dimethyl-3-nitro-5,6,7,8-tetrahydro-1,6-naphthyridine; 570409-62-0; 1,6-Naphthyridine-6(5H)-carboxylic acid, 7,8-dihydro-8,8-dimethyl-3-nitro-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 8,8-Dimethyl-3-Nitro-7,8-Dihydro-1,6-Naphthyridine-6(5H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and other relevant techniques are provided to guarantee traceability and batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.