Description

(+)-1,2-Bis((2R,5R)-2,5-Di-I-Propylphospholano)Benzene)1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate is a high-purity, chiral transition metal complex widely recognized as a highly efficient asymmetric hydrogenation catalyst. Its primary value lies in enabling the production of enantiomerically pure intermediates and active pharmaceutical ingredients (APIs) with exceptional selectivity and yield. This catalyst is essential for R&D and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in their synthetic processes.

Application

• Asymmetric Hydrogenation Catalyst: For the enantioselective reduction of prochiral olefins, ketones, and imines in fine chemical synthesis.
• Pharmaceutical Intermediate Synthesis: Critical in the production of chiral building blocks for APIs, including β-amino acids, unnatural amino acids, and other bioactive molecules.
• Agrochemical Manufacturing: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Flavor and Fragrance Industry: Applied in the creation of chiral aroma chemicals and flavor compounds.
• Academic and Industrial R&D: A valuable tool for methodology development and process chemistry research in asymmetric catalysis.
• Process Scale-up: Suitable for optimization and scaling of catalytic hydrogenation reactions from laboratory to pilot plant and commercial production.

Basic Information

Product Name	(+)-1,2-Bis((2R,5R)-2,5-Di-I-Propylphospholano)Benzene)1,5-Cyclooctadiene)Rhodium (I) Tetrafluoroborate
CAS No.	569650-64-2
Molecular Formula	C34H56BF4P2Rh
Molecular Weight	716.45 g/mol
Synonyms	(R,R)-DuanPhos-Rh(COD)BF4; (R,R)-1,2-Bis((2R,5R)-2,5-diisopropylphospholano)benzene)(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; DuanPhos Rh(I) catalyst; Rh-(R,R)-DuanPhos(COD)BF4; Asymmetric Hydrogenation Catalyst with DuanPhos ligand; [Rh((R,R)-DuanPhos)(COD)]BF4; (R,R)-DuanPhos-Rh(COD) Tetrafluoroborate
EINECS	Contact for details

Quality Control

Our high-value chiral catalysts are produced and handled under strict quality protocols to ensure batch-to-batch consistency and optimal catalytic performance. Each lot undergoes comprehensive analysis including NMR (1H, 31P, 19F) for structural confirmation and purity, HPLC for chiral purity assessment, and elemental analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific rotation is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. The product is moisture-sensitive and should be handled in a dry environment. For long-term stability, keep the original container sealed and desiccated.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (NMR)	Conforms to structure
Purity (NMR)	≥ 97%
Chiral Purity (HPLC)	≥ 99% ee
Specific Rotation [α]	Contact for details
Moisture Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.