Description

1,2,3,4-Tetrahydro-2-Oxo-Quinoline-8-Carboxylic Acid is a high-purity, versatile heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its unique fused quinoline structure makes it a critical intermediate for developing novel pharmacologically active compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the research and development of advanced organic materials, including ligands for catalysis and components for organic electronics.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic and medicinal chemistry.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, dyes, and complex natural product analogs.

Basic Information

Product Name	1,2,3,4-Tetrahydro-2-Oxo-Quinoline-8-Carboxylic Acid
CAS No.	569344-28-1
Molecular Formula	C10H9NO3
Molecular Weight	191.18 g/mol
Synonyms	8-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-2-oxo-; 2-Oxo-1,2,3,4-tetrahydroquinoline-8-carboxylic acid; THQ-8-COOH; 1,2,3,4-Tetrahydro-2-oxoquinoline-8-carboxylic acid; 2-Oxotetrahydroquinoline-8-carboxylic acid; 8-Carboxy-1,2,3,4-tetrahydro-2-quinolone; 1,2,3,4-Tetrahydrocarbostyril-8-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-2-Oxo-Quinoline-8-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.