Description

4-(4-Fluoro-Phenylsulfanyl)-3-Nitro-Benzoic Acid is a high-purity, synthetically valuable aromatic compound featuring a nitro-substituted benzoic acid core linked via a thioether bridge to a fluorinated phenyl ring. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the nitro and fluoro substituents.
• Material Science Chemistry: Used in the research and development of advanced polymers, liquid crystals, and organic electronic materials due to its conjugated system and functional groups.
• Medicinal Chemistry & Drug Discovery: Employed in high-throughput screening and combinatorial chemistry to create libraries of compounds for hit identification and lead optimization.
• Custom Synthesis & Contract Manufacturing: A crucial starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards for clinical trial material production.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-ligand interactions.

Basic Information

Product Name	4-(4-Fluoro-Phenylsulfanyl)-3-Nitro-Benzoic Acid
CAS No.	565177-99-3
Molecular Formula	C₁₃H₈FNO₄S
Molecular Weight	293.27 g/mol
Synonyms	3-Nitro-4-[(4-fluorophenyl)thio]benzoic acid; 4-[(4-Fluorophenyl)sulfanyl]-3-nitrobenzoic acid; Benzoic acid, 4-[(4-fluorophenyl)thio]-3-nitro-; 4-(4-Fluorophenylthio)-3-nitrobenzoic acid; 4-(p-Fluorophenylthio)-3-nitrobenzoic acid; 4-(4-Fluorobenzenesulfanyl)-3-nitro-benzoic acid; 565177-99-3; 4-(4-Fluorophenylsulfanyl)-3-nitrobenzoic acid
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Fluoro-Phenylsulfanyl)-3-Nitro-Benzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive (store away from light) and should be handled under inert atmosphere for long-term storage to prevent potential degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.