Description

1-((4-(tert-Butyl)Phenyl)Sulfonyl)-6-Methyl-1,2,3,4-Tetrahydroquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its sulfonamide-linked tetrahydroquinoline core structure. This compound is critical for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery, process development, and scale-up production.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates, especially in medicinal chemistry programs.
• Drug Discovery & Development: Serves as a versatile scaffold for creating libraries of novel compounds for high-throughput screening and lead optimization.
• Chemical Biology Research: Used as a probe or tool compound to study biological pathways and protein-ligand interactions.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale manufacturing of target APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis projects.

Basic Information

Product Name	1-((4-(tert-Butyl)Phenyl)Sulfonyl)-6-Methyl-1,2,3,4-Tetrahydroquinoline
CAS No.	562079-21-4
Molecular Formula	C20H25NO2S
Molecular Weight	343.48 g/mol
Synonyms	6-Methyl-1-[(4-tert-butylphenyl)sulfonyl]-1,2,3,4-tetrahydroquinoline; 1-(4-tert-Butylbenzenesulfonyl)-6-methyl-1,2,3,4-tetrahydroquinoline; N-[(4-tert-Butylphenyl)sulfonyl]-6-methyl-1,2,3,4-tetrahydroquinoline; 1-(p-tert-Butylphenylsulfonyl)-6-methyl-1,2,3,4-tetrahydroquinoline; 6-Methyl-1-(4-(tert-butyl)phenylsulfonyl)-1,2,3,4-tetrahydroquinoline; Tetrahydroquinoline sulfonamide derivative; BTSMTHQ
EINECS	Contact for details

Quality Control

Our 1-((4-(tert-Butyl)Phenyl)Sulfonyl)-6-Methyl-1,2,3,4-Tetrahydroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.