Description

Dihydronormorphine 6-β-D-Glucuronide is a high-purity reference standard and metabolite of clinical significance. This compound is essential for analytical research and method development in forensic and clinical toxicology laboratories. It is primarily utilized by pharmaceutical researchers and diagnostic manufacturers for the precise quantification of opioid metabolites in biological matrices.

Application

• Analytical Reference Standard: Primary use as a certified reference material (CRM) for calibrating HPLC, LC-MS/MS, and GC-MS systems in bioanalytical testing.
• Forensic Toxicology: Critical for the accurate identification and quantification of dihydronormorphine and related opioid metabolites in forensic casework and workplace drug testing.
• Clinical Research & Pharmacokinetics: Used in studies to understand the metabolism, distribution, and excretion of opioid drugs in human and animal models.
• Diagnostic Kit Development: Serves as a key component in the development and validation of immunoassays and other diagnostic tests for opioid abuse.
• Pharmaceutical Impurity Profiling: Employed in the quality control of opioid-based pharmaceuticals to monitor and quantify specific glucuronidated metabolites.
• Metabolite Synthesis & Study: Acts as a precursor or intermediate in the synthesis and study of other opioid phase II metabolites.

Basic Information

Product Name	Dihydronormorphine 6-β-D-Glucuronide
CAS No.	561323-10-2
Molecular Formula	C23H29NO9
Molecular Weight	463.48 g/mol
Synonyms	Dihydronormorphine 6-Glucuronide; 6β-D-Glucopyranosiduronic acid, 4,5α-epoxy-17-methyl-7,8-dihydromorphinan-3,6α-diol; Normorphine-6-glucuronide (dihydro); Dihydronormorphine-6-β-D-glucuronide; 6-β-Glucuronide of dihydronormorphine; Dihydro-normorphine-6-glucuronide
EINECS	Contact for details

Quality Control

Our Dihydronormorphine 6-β-D-Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC purity analysis and structural confirmation (NMR, MS), to ensure identity, potency, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every lot to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.