Description

1,2,8-Triazaspiro[4.5]Decan-3-One is a high-purity, heterocyclic organic compound featuring a unique spirocyclic structure that combines piperidine and triazolone motifs. This specialized molecular architecture makes it a valuable and versatile pharmaceutical intermediate and research chemical for advanced synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Agrochemical Research: Serves as a precursor for developing new herbicides, fungicides, and insecticides with potentially novel modes of action.
• Chemical Biology Probe: Used in medicinal chemistry and chemical biology to study enzyme inhibition and protein-ligand interactions due to its spirocyclic scaffold.
• Material Science: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the discovery of new chemical entities.
• Fine Chemical Synthesis: Acts as a sophisticated synthon for constructing complex, nitrogen-containing heterocycles in multi-step organic syntheses.

Basic Information

Product Name	1,2,8-Triazaspiro[4.5]Decan-3-One
CAS No.	561314-54-3
Molecular Formula	C8H13N3O
Molecular Weight	167.21 g/mol
Synonyms	1,2,8-Triazaspiro[4.5]decan-3-one; 3H-1,2,8-Triazaspiro[4.5]decan-3-one; 8-Azaspiro[4.5]decane-7,9-dione hydrazone; Spiro[piperidine-4,5'-[1,2,4]triazol]-3'-one
EINECS	Contact for details

Quality Control

Our 1,2,8-Triazaspiro[4.5]Decan-3-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to ensure product stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.