Description

Spiro[Bicyclo[3.2.1]Octane-8,2-[1,3]Dioxolan]-3-Amine, n-Methyl-, Stereoisomer (9Ci) CAS NO 561307-39-9 is a specialized spirocyclic amine derivative, a high-value building block in advanced organic synthesis. Its unique, rigid molecular framework makes it a critical intermediate for constructing complex, three-dimensional pharmacophores. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients with enhanced selectivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel central nervous system (CNS) active drugs, antiviral agents, and other therapeutic candidates.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where its spirocyclic structure can contribute to unique modes of action and environmental persistence profiles.
• Ligand & Catalyst Development: Serves as a precursor for sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Potential monomer or additive for creating specialty polymers with specific thermal or mechanical properties.
• Academic & R&D: A valuable tool for methodological studies in organic chemistry, particularly in spirocycle formation and stereoselective transformations.

Basic Information

Product Name	Spiro[Bicyclo[3.2.1]Octane-8,2-[1,3]Dioxolan]-3-Amine, n-Methyl-, Stereoisomer (9Ci)
CAS No.	561307-39-9
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	N-Methylspiro[bicyclo[3.2.1]octane-8,2'-[1,3]dioxolan]-3-amine; 3-(Methylamino)spiro[bicyclo[3.2.1]octane-8,2'-[1,3]dioxolane]; Spirocyclic N-methyl amine derivative; 561307-39-9; (Stereoisomer of Spirocyclic Amine); Bicyclic Spiroketal Amine; Advanced Pharmaceutical Intermediate
EINECS	Contact for details

Quality Control

Every batch of our Spiro[Bicyclo[3.2.1]Octane-8,2-[1,3]Dioxolan]-3-Amine, n-Methyl-, Stereoisomer (9Ci) is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity for your critical R&D and scale-up processes. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and impurity profiles are available upon request and are aligned with cGMP principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.