Description

2-Amino-6-(Trifluoromethoxy)Benzoic Acid is a high-value fluorinated aromatic building block, distinguished by its unique combination of an amino group and a trifluoromethoxy substituent on the benzoic acid core. This structure makes it a critical intermediate for synthesizing advanced pharmaceutical compounds and agrochemicals, where the trifluoromethoxy group is prized for enhancing metabolic stability and lipophilicity. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides where the trifluoromethoxy moiety improves biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials for enhanced performance.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Amino-6-(Trifluoromethoxy)Benzoic Acid
CAS No.	561304-48-1
Molecular Formula	C8H6F3NO3
Molecular Weight	221.14 g/mol
Synonyms	6-Amino-2-(trifluoromethoxy)benzoic acid; Benzoic acid, 2-amino-6-(trifluoromethoxy)-; 2-Amino-6-(trifluoromethoxy)benzoic acid; 2-Amino-α,α,α-trifluoro-p-anisic acid; 6-(Trifluoromethoxy)anthranilic acid; 2-Carboxy-3-amino-α,α,α-trifluoroanisole
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-6-(Trifluoromethoxy)Benzoic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets your precise R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.