Description

(1R,2R)-2-(Benzyloxymethyl)Cyclopropanecarboxylic Acid is a high-purity chiral cyclopropane derivative, a crucial advanced pharmaceutical intermediate (API) and building block in asymmetric synthesis. Its value lies in its stereochemically defined cyclopropane ring, a structural motif prized for its ability to impart metabolic stability and conformational rigidity to drug molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries developing novel therapeutics, particularly in areas like antiviral, anticancer, and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex, biologically active molecules and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used in stereoselective reactions to construct molecules with specific three-dimensional configurations critical for drug efficacy.
• Medicinal Chemistry Research: Serves as a core scaffold in drug discovery programs for probing structure-activity relationships (SAR).
• Protease Inhibitor Development: The cyclopropane carboxylic acid moiety is a common feature in the design of inhibitors for various enzyme targets.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and fragrances requiring chiral precision.
• Ligand and Catalyst Preparation: Can be utilized to develop novel chiral ligands or organocatalysts for catalytic processes.

Basic Information

Product Name	(1R,2R)-2-(Benzyloxymethyl)Cyclopropanecarboxylic Acid
CAS No.	561055-27-4
Molecular Formula	C12H14O3
Molecular Weight	206.24 g/mol
Synonyms	(1R,2R)-2-[(Benzyloxy)methyl]cyclopropanecarboxylic Acid; (1R,2R)-2-(Benzyloxymethyl)cyclopropanecarboxylic Acid; (1R,2R)-rel-2-[(Phenylmethoxy)methyl]cyclopropanecarboxylic Acid; Cyclopropanecarboxylic acid, 2-[(phenylmethoxy)methyl]-, (1R,2R)-rel-; (1R-cis)-2-[(Benzyloxy)methyl]cyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our (1R,2R)-2-(Benzyloxymethyl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.