Description

2-Propanone, 1-(Methylsulfinyl)-, (-)- (9Ci) is a chiral, sulfur-containing ketone derivative of acetone, characterized by its methylsulfinyl functional group. This compound is a valuable chiral synthon and building block in advanced organic synthesis, particularly for the preparation of enantiomerically pure pharmaceuticals and fine chemicals. It is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, optically active intermediates for asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in catalytic and stoichiometric asymmetric reactions to induce enantioselectivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in metal-catalyzed transformations.
• Agrochemical Research: Employed in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances where optical purity is critical.
• Academic and R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	2-Propanone, 1-(Methylsulfinyl)-, (-)- (9Ci)
CAS No.	560094-62-4
Molecular Formula	C4H8O2S
Molecular Weight	120.17 g/mol
Synonyms	(-)-1-(Methylsulfinyl)acetone; (S)-1-(Methylsulfinyl)acetone; 1-(Methylsulfinyl)propan-2-one; 1-(Methylsulfinyl)acetone; Acetone, 1-(methylsulfinyl)-, (-)-; Chiral methylsulfinyl acetone; (S)-1-(Methylsulfinyl)-2-propanone
EINECS	Contact for details

Quality Control

Our production of 2-Propanone, 1-(Methylsulfinyl)-, (-)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high optical purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, NMR, and GC to confirm identity, enantiomeric excess (ee), and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting compliance in cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.