Description

7-(Trifluoromethyl)Quinolin-5-Ol is a high-purity fluorinated quinoline derivative, a critical advanced intermediate in modern organic synthesis. Its value lies in the unique electronic properties imparted by the trifluoromethyl group, which is essential for modulating the biological activity and physicochemical characteristics of target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel agrochemicals, pharmaceuticals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of potential drug candidates, particularly in areas targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the CF3 group enhances lipophilicity and metabolic stability.
• Material Science: Acts as a precursor for organic light-emitting diodes (OLEDs) and other electronic materials due to its electron-withdrawing character and potential for charge transport.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis, including those used in cross-coupling and asymmetric synthesis.
• Chemical Biology Probe Development: Utilized as a core scaffold for creating fluorescent tags or bioactive probes to study biological pathways.

Basic Information

Product Name	7-(Trifluoromethyl)Quinolin-5-Ol
CAS No.	558479-28-0
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	5-Hydroxy-7-(trifluoromethyl)quinoline; 7-(Trifluoromethyl)-5-quinolinol; 5-Quinolinol, 7-(trifluoromethyl)-; 7-Trifluoromethylquinolin-5-ol; 7-Trifluoromethyl-5-hydroxyquinoline; Quinolin-5-ol, 7-(trifluoromethyl)-; 558479-28-0; 7-(Trifluoromethyl)-5-hydroxyquinoline
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)Quinolin-5-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.