Description

tert-Butyl (1R,4R)-4-(5,6,7,8-Tetrahydroquinolin-8-Ylamino)Cyclohexylcarbamate is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. This compound, identified by CAS number 558442-80-1, is valued for its role as a key building block in the development of novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the discovery and process development of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• API Process Development: Used in the research, development, and scale-up of manufacturing routes for complex active pharmaceutical ingredients.
• Asymmetric Synthesis: Serves as a key starting material or intermediate in stereoselective chemical reactions to create enantiomerically pure compounds.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.
• Pre-clinical & Clinical Trial Material: Used to produce material for pre-clinical studies and early-phase clinical trials.

Basic Information

Product Name	tert-Butyl (1R,4R)-4-(5,6,7,8-Tetrahydroquinolin-8-Ylamino)Cyclohexylcarbamate
CAS No.	558442-80-1
Molecular Formula	C21H31N3O2
Molecular Weight	357.49 g/mol
Synonyms	(1R,4R)-4-[[(8S)-5,6,7,8-Tetrahydroquinolin-8-yl]amino]cyclohexyl carbamic acid tert-butyl ester; tert-Butyl N-[(1R,4R)-4-[[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]amino]cyclohexyl]carbamate; (1R,4R)-4-((S)-5,6,7,8-Tetrahydroquinolin-8-ylamino)cyclohexylcarbamic acid tert-butyl ester; Boc-Protected (1R,4R)-4-((S)-5,6,7,8-Tetrahydroquinolin-8-ylamino)cyclohexylamine; 558442-80-1; UNII-7H1Q1F2W0Y
EINECS	Contact for details

Quality Control

Our tert-Butyl (1R,4R)-4-(5,6,7,8-Tetrahydroquinolin-8-Ylamino)Cyclohexylcarbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.