Description

2,4-Dibromo-3-Fluoro-Nitrobenzene is a high-purity halogenated nitrobenzene derivative, serving as a critical multi-functional building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for complex coupling and functionalization reactions.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those containing halogenated aromatic systems for targeted biological activity.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the bromo and fluoro substituents enhance stability and efficacy.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination due to the presence of bromine atoms.
• Chemical Synthesis Building Block: Utilized for nucleophilic aromatic substitution (SNAr) reactions, where the nitro and halogen groups provide multiple sites for derivatization.
• Dye and Pigment Intermediate: Employed in the synthesis of complex halogenated dyes and pigments for high-performance applications.

Basic Information

Product Name	2,4-Dibromo-3-Fluoro-Nitrobenzene
CAS No.	557789-62-5
Molecular Formula	C6H2Br2FNO2
Molecular Weight	298.89 g/mol
Synonyms	1,2-Dibromo-4-fluoro-5-nitrobenzene; 3-Fluoro-2,4-dibromonitrobenzene; Benzene, 1,2-dibromo-4-fluoro-5-nitro-; 2,4-Dibromo-3-fluoronitrobenzene; 4-Fluoro-3,5-dibromonitrobenzene
EINECS	Contact for details

Quality Control

Every batch of 2,4-Dibromo-3-Fluoro-Nitrobenzene is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the high standards required for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable consistency and traceability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber glass, or in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.