Description

Spiro[4.5]Decan-2-One, 4,8-Dimethyl-1-Methylene- (9Ci) is a specialized spirocyclic ketone building block of significant interest in advanced organic synthesis. Its unique bridged, sterically defined structure makes it a valuable precursor for creating complex molecular architectures with specific three-dimensional properties. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, fragrance development, and material science.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where its spirocyclic core can contribute to unique biological activity and stability.
• Fragrance & Flavor Chemistry: Acts as a precursor for musky or woody odorants, leveraging its complex, multi-ring structure to create novel scent molecules.
• Material Science: Investigated as a monomer or cross-linking agent for producing polymers with tailored thermal and mechanical properties.
• Catalyst & Ligand Development: Provides a rigid backbone for the design of novel asymmetric catalysts and chiral ligands used in stereoselective synthesis.
• Academic & R&D: Employed in fundamental organic chemistry research to study reaction mechanisms and develop new synthetic methodologies involving strained ring systems.

Basic Information

Product Name	Spiro[4.5]Decan-2-One, 4,8-Dimethyl-1-Methylene- (9Ci)
CAS No.	557785-36-1
Molecular Formula	C13H20O
Molecular Weight	192.30 g/mol
Synonyms	4,8-Dimethyl-1-methylenespiro[4.5]decan-2-one; 1-Methylene-4,8-dimethylspiro[4.5]decan-2-one; Spiro[4.5]decan-2-one, 4,8-dimethyl-1-methylene-; 4,8-Dimethyl-1-methylenespiro[4.5]decan-2-one (9CI)
EINECS	Contact for details

Quality Control

Every batch of Spiro[4.5]Decan-2-One, 4,8-Dimethyl-1-Methylene- (9Ci) is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to support cGMP and ISO-guided applications where documentation and traceability are critical.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.