Description

Spiro[4.5]Decan-2-One, 4,6-Dimethyl-1-Methylene-, (4R,5R,6S)-Rel- (9Ci) is a high-purity, stereochemically defined spirocyclic ketone building block. This compound is valued for its rigid, three-dimensional structure, which is critical for imparting specific conformational properties in advanced molecular design. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in constructing complex molecular scaffolds for next-generation pesticides and herbicides with enhanced activity and selectivity.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals where the spirocyclic core influences material properties.
• Asymmetric Catalysis Ligand Precursor: The defined stereocenters make it a valuable starting point for developing novel chiral ligands and organocatalysts.
• Flavor & Fragrance Chemistry: Potential use in synthesizing novel musk compounds or other complex aroma chemicals due to its unique structural motif.
• Academic & R&D Laboratories: A valuable tool for methodological studies in organic synthesis, including cyclization and stereoselective transformation reactions.

Basic Information

Product Name	Spiro[4.5]Decan-2-One, 4,6-Dimethyl-1-Methylene-, (4R,5R,6S)-Rel- (9Ci)
CAS No.	557785-32-7
Molecular Formula	C13H20O
Molecular Weight	192.30 g/mol
Synonyms	rel-(4R,5R,6S)-4,6-Dimethyl-1-methylenespiro[4.5]decan-2-one; (4R,5R,6S)-4,6-Dimethyl-1-methylenespiro[4.5]decan-2-one (relative configuration); 4,6-Dimethyl-1-methylenespiro[4.5]decan-2-one; Spiro[4.5]decan-2-one, 4,6-dimethyl-1-methylene-, (4R,5R,6S)-rel-; 1-Methylene-4,6-dimethylspiro[4.5]decan-2-one
EINECS	Contact for details

Quality Control

Every batch of Spiro[4.5]Decan-2-One, 4,6-Dimethyl-1-Methylene-, (4R,5R,6S)-Rel- (9Ci) is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, typically including chiral HPLC analysis. A Certificate of Analysis (COA) detailing specifications such as assay (by GC/HPLC), enantiomeric excess, and impurity profile is available for each lot upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.