Description

4-Amino-3-Bromo-5-Nitrobenzoic Acid is a high-purity, multi-functional aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring three distinct functional groups (amino, bromo, and nitro) on a benzoic acid core, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in the synthesis of complex heterocycles and targeted small molecules.
• Agrochemical Synthesis: Serves as a crucial building block in the creation of advanced herbicides, fungicides, and plant growth regulators.
• Dye and Pigment Manufacturing: Used in the synthesis of specialized azo dyes and high-performance pigments due to its reactive bromo and amino groups.
• Material Science Research: Employed in the development of organic semiconductors, metal-organic frameworks (MOFs), and other functional materials.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig aminations.
• Chemical Derivatization: The carboxylic acid, amino, and nitro groups allow for extensive functionalization to create custom libraries of compounds for screening.

Basic Information

Product Name	4-Amino-3-Bromo-5-Nitrobenzoic Acid
CAS No.	556651-33-3
Molecular Formula	C7H5BrN2O4
Molecular Weight	261.03 g/mol
Synonyms	3-Bromo-4-amino-5-nitrobenzoic acid; Benzoic acid, 4-amino-3-bromo-5-nitro-; 4-Amino-3-bromo-5-nitro-benzoic acid; 5-Nitro-3-bromo-4-aminobenzoic acid; 3-Bromo-5-nitroanthranilic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-3-Bromo-5-Nitrobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.