Description

5-Bromo-2,3-Dihydrospiro[Imidazolidine-4,1-Indene]-2,5-Dione is a specialized spirocyclic heterocyclic compound featuring a fused imidazolidine-indene structure. This molecule serves as a high-value synthetic intermediate and building block in advanced organic synthesis, prized for its unique three-dimensional architecture and bromine functionality. It is primarily utilized by pharmaceutical R&D and agrochemical laboratories for the development of novel active ingredients and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring spirocyclic motifs for optimal receptor binding.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or insecticides where the brominated spiro structure confers specific biological activity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and cyclization processes to construct complex heterocyclic systems for material science and chemical biology.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.
• Academic and Industrial R&D: A valuable compound for methodological studies in synthetic chemistry and for exploring new chemical spaces in discovery programs.

Basic Information

Product Name	5-Bromo-2,3-Dihydrospiro[Imidazolidine-4,1-Indene]-2,5-Dione
CAS No.	553680-99-2
Molecular Formula	C11H9BrN2O2
Molecular Weight	281.11 g/mol
Synonyms	5-Bromospiro[imidazolidine-4,1'-indene]-2,5-dione; 5-Bromo-1,3-diazaspiro[4.5]decane-2,4-dione (related structural name); 5-Bromo-2,3-dihydro-1H-spiro[imidazolidine-4,1'-indene]-2,5-dione; 5-Bromospiro(imidazolidine-4,1'-indene)-2,5-dione; BRD (common abbreviation); CAS 553680-99-2; Spirocyclic bromoimidazolidinedione
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,3-Dihydrospiro[Imidazolidine-4,1-Indene]-2,5-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.