Description

7-Oxa-2-Azaspiro[3.5]Nonane, 2-[(4-Methylphenyl)Sulfonyl]- is a high-value, spirocyclic sulfonamide building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique constrained bicyclic structure can impart desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical scaffold in medicinal chemistry for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its spirocyclic core for enhanced efficacy and selectivity.
• Chemical Biology Probe: Serves as a versatile building block for creating molecular probes to study enzyme function and protein-protein interactions.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers and advanced materials with specific functional properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this specialized heterocycle.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental research in synthetic methodology and heterocyclic chemistry.

Basic Information

Product Name	7-Oxa-2-Azaspiro[3.5]Nonane, 2-[(4-Methylphenyl)Sulfonyl]-
CAS No.	550371-66-9
Molecular Formula	C14H19NO3S
Molecular Weight	281.37 g/mol
Synonyms	2-(p-Tolylsulfonyl)-7-oxa-2-azaspiro[3.5]nonane; 2-(4-Methylbenzenesulfonyl)-7-oxa-2-azaspiro[3.5]nonane; 2-Tosyl-7-oxa-2-azaspiro[3.5]nonane; 7-Oxa-2-azaspiro[3.5]nonane-2-sulfonic acid (4-methylphenyl) ester; N-Tosyl-7-oxa-2-azaspiro[3.5]nonane; Spirocyclic Sulfonamide Intermediate
EINECS	Contact for details

Quality Control

Our 7-Oxa-2-Azaspiro[3.5]Nonane, 2-[(4-Methylphenyl)Sulfonyl]- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the stringent requirements of our global pharmaceutical and agrochemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.