Description

4'- (Hydroxymethyl)Octahydrospiro[Cyclohe Xane-1,2'-[1,3]Dioxolo[4,5-D]Pyrano[3,2- B]Pyran]-8'-Yl)Acetate is a complex spirocyclic and fused pyran derivative, a high-purity advanced pharmaceutical intermediate (API) with significant synthetic utility. Its intricate molecular architecture makes it a valuable building block for the research and development of novel therapeutic agents, particularly in complex molecule synthesis. This compound is primarily targeted at pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, especially in areas requiring sophisticated chiral and polycyclic frameworks.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential active pharmaceutical ingredients (APIs) with complex stereochemistry.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in drug discovery programs targeting various diseases.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target molecules in pilot plants.
• Asymmetric Synthesis: Utilized in chiral synthesis due to its inherent stereocenters and spirocyclic structure, aiding in the creation of enantiomerically pure compounds.
• Natural Product Analog Synthesis: Acts as a synthetic analog or intermediate for the preparation of compounds related to complex natural products containing fused pyran rings.
• Chemical Biology Probes: Can be functionalized to create molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	4'- (Hydroxymethyl)Octahydrospiro[Cyclohe Xane-1,2'-[1,3]Dioxolo[4,5-D]Pyrano[3,2- B]Pyran]-8'-Yl)Acetate
CAS No.	546141-23-5
Molecular Formula	C18H28O7
Molecular Weight	356.41 g/mol
Synonyms	4'-(Hydroxymethyl)octahydrospiro[cyclohexane-1,2'-[1,3]dioxolo[4,5-d]pyrano[3,2-b]pyran]-8'-yl acetate; Spiro[cyclohexane-1,2'-[1,3]dioxolo[4,5-d]pyrano[3,2-b]pyran]-8'-yl acetate, 4'-(hydroxymethyl)octahydro-; Acetic acid 4'-(hydroxymethyl)octahydrospiro[cyclohexane-1,2'-[1,3]dioxolo[4,5-d]pyrano[3,2-b]pyran]-8'-yl ester; CAS 546141-23-5
EINECS	Contact for details

Quality Control

Our 4'- (Hydroxymethyl)Octahydrospiro[Cyclohe Xane-1,2'-[1,3]Dioxolo[4,5-D]Pyrano[3,2- B]Pyran]-8'-Yl)Acetate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, NMR, and other relevant spectroscopic methods. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and cGMP environments where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Any individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.