Description

2-Pyrrolidinemethanamine,N,1-Diethyl-,(2S)-(9Ci) CAS NO 546114-75-4 is a high-purity, chiral pyrrolidine derivative, specifically the (S)-enantiomer of a diethyl-substituted aminomethylpyrrolidine. This compound matters as a sophisticated chiral building block and ligand, offering precise stereochemical control critical for the development of active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for asymmetric synthesis, catalysis, and the creation of novel molecular entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug molecules, particularly for central nervous system (CNS) targets and receptor modulators.
• Catalyst Ligand: Serves as a precursor for chiral ligands used in transition metal catalysis (e.g., for asymmetric hydrogenation or C-C bond formation).
• Agrochemical Research: Employed in the development of enantiomerically pure pesticides and herbicides where specific stereochemistry impacts biological activity.
• Chemical Biology Probe: Used to create tool compounds for studying enzyme mechanisms and protein-ligand interactions due to its defined stereocenter and amine functionality.
• Material Science: A monomer or modifier in the synthesis of specialty polymers with tailored optical or mechanical properties.
• Academic & Process R&D: A valuable reagent for methodological development in organic synthesis and scale-up process optimization in fine chemical production.

Basic Information

Product Name	2-Pyrrolidinemethanamine,N,1-Diethyl-,(2S)-(9Ci)
CAS No.	546114-75-4
Molecular Formula	C9H20N2
Molecular Weight	156.27 g/mol
Synonyms	(S)-1-Diethylaminomethylpyrrolidine; (S)-2-((Diethylamino)methyl)pyrrolidine; (S)-N,N-Diethyl-1-pyrrolidinemethanamine; (2S)-1-(Diethylaminomethyl)pyrrolidine; (S)-1-(Diethylaminomethyl)pyrrolidine; (S)-N,N-Diethylpyrrolidin-2-ylmethanamine; 546114-75-4; (S)-Aminomethylpyrrolidine Diethyl Derivative
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinemethanamine,N,1-Diethyl-,(2S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.