Description

2',6'-Dibromo-4'-(trifluoromethyl)acetanilide is a high-purity, multi-functional halogenated aromatic intermediate of significant importance in advanced organic synthesis. Its unique molecular structure, featuring bromine and trifluoromethyl substituents, makes it a valuable building block for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a critical building block for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the bromine and trifluoromethyl groups.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic core.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and pigments where halogen atoms enhance lightfastness and color properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl systems, a common motif in medicinal chemistry.

Basic Information

Product Name	2',6'-Dibromo-4'-(Trifluoromethyl)Acetanilide
CAS No.	544716-06-5
Molecular Formula	C9H6Br2F3NO
Molecular Weight	369.96 g/mol
Synonyms	N-(2,6-Dibromo-4-(trifluoromethyl)phenyl)acetamide; 2',6'-Dibromo-4'-trifluoromethylacetanilide; 2,6-Dibromo-α,α,α-trifluoro-p-acetotoluidide; Acetamide, N-[2,6-dibromo-4-(trifluoromethyl)phenyl]-; N-(2,6-Dibromo-4-trifluoromethylphenyl)acetamide
EINECS	Contact for details

Quality Control

Our 2',6'-Dibromo-4'-(trifluoromethyl)acetanilide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.