Description

(S)-n-{1-[2-(Trifluoromethyl)Phenyl]Ethyl}Methylamine, 98% Min. is a high-purity chiral amine building block featuring a trifluoromethylphenyl group, offering unique steric and electronic properties. This compound is critical for pharmaceutical and agrochemical research, where its defined stereochemistry and fluorine content are leveraged to modulate the biological activity, metabolic stability, and lipophilicity of target molecules. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances bioactivity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands in asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials that require fluorinated aromatic components.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study enzyme mechanisms and receptor interactions.

Basic Information

Product Name	(S)-n-{1-[2-(Trifluoromethyl)Phenyl]Ethyl}Methylamine, 98% Min.
CAS No.	541539-66-6
Molecular Formula	C10H12F3N
Molecular Weight	203.21 g/mol
Synonyms	(S)-1-[2-(Trifluoromethyl)phenyl]ethylmethylamine; (S)-α-Methyl-2-(trifluoromethyl)benzeneethanamine; (S)-N-Methyl-1-[2-(trifluoromethyl)phenyl]ethanamine; (S)-1-(2-Trifluoromethylphenyl)ethylmethylamine; (S)-N-Methyl-α-methyl-2-(trifluoromethyl)benzeneethanamine; (S)-N,1-Dimethyl-1-[2-(trifluoromethyl)phenyl]ethanamine; (S)-2-(Trifluoromethyl)phenethylamine, N-methyl derivative
EINECS	Contact for details

Quality Control

Our (S)-n-{1-[2-(Trifluoromethyl)Phenyl]Ethyl}Methylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the specified 98% minimum purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, assay, impurity profile, and specific rotation. Our quality commitment supports cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	98.0% Min.
Chiral Purity (Chiral HPLC)	99.0% Min. (S)-enantiomer
Water Content (KF)	0.5% Max.
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.