Description

6-Iodo-n-(3-Methyl-4-((6-Methylpyridin-3-Yl)Oxy)Phenyl)Quinazolin-4-Amine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, particularly for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted oncology drugs, especially tyrosine kinase inhibitors.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in vitro and in vivo to study specific biological pathways and enzyme inhibition mechanisms.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create complex molecules for high-value applications.
• Reference Standard: Provides a certified material for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	6-Iodo-n-(3-Methyl-4-((6-Methylpyridin-3-Yl)Oxy)Phenyl)Quinazolin-4-Amine
CAS No.	537705-05-8
Molecular Formula	C21H17IN4O
Molecular Weight	492.29 g/mol
Synonyms	6-Iodo-N-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]-4-quinazolinamine; 4-Quinazolinamine, 6-iodo-N-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]-; UNII-9V6S5A8R4S; 9V6S5A8R4S; BDBM50112657; AKOS015915889; CTK8C8073; ZINC000004079756
EINECS	Contact for details

Quality Control

Every batch of 6-Iodo-n-(3-Methyl-4-((6-Methylpyridin-3-Yl)Oxy)Phenyl)Quinazolin-4-Amine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.