Description

Besilesomab is a monoclonal antibody fragment used for diagnostic imaging. This compound is critical for the specific targeting and visualization of inflammatory sites within the body. It is primarily required by pharmaceutical manufacturers, clinical research organizations, and diagnostic imaging centers developing or utilizing advanced immunoscintigraphy agents. The product is supplied under stringent quality controls to ensure reliability for sensitive diagnostic applications.

Application

• Immunoscintigraphy Agent: Used in nuclear medicine for the detection and localization of infection and inflammation, particularly in cases of osteomyelitis.
• Diagnostic Imaging: Serves as a targeting moiety for radiolabeling (e.g., with Technetium-99m) to create radiopharmaceuticals for SPECT imaging.
• Clinical Research: Employed in studies investigating inflammatory diseases and the efficacy of antibody-based diagnostic tools.
• Pharmaceutical Development: Acts as a key intermediate or reference standard in the development and quality control of novel diagnostic antibodies.

Basic Information

Product Name	Besilesomab
CAS No.	537694-98-7
Molecular Formula	C6480H10006N1736O2016S46
Molecular Weight	~145.9 kDa
Synonyms	Besilesomab; BW 250/183; Anti-NCA-95 Fab' Fragment; Granulocyte-Specific Monoclonal Antibody Fragment; NCA-95 Antibody Fab' Fragment; Immunoglobulin G1, anti-(human granulocyte cell surface antigen CD66) (human-mouse monoclonal BW 250/183 γ1-chain), Fab fragment; Scintimun
EINECS	Contact for details

Quality Control

Our Besilesomab is manufactured and tested to meet exacting standards for diagnostic and research use. Quality assurance includes rigorous testing for identity, purity, potency, and biological activity. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results from tests including SDS-PAGE, HPLC, endotoxin levels, and sterility where applicable. We adhere to relevant GMP guidelines for the production of biopharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under controlled conditions to prevent degradation. For specific storage and handling protocols, refer to the accompanying technical data sheet.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear solution
Identification (HPLC/CE-SDS)	Conforms to reference standard
Purity (SDS-PAGE, HPLC)	≥ 95% (Monomeric Fab' fragment)
Protein Content (UV)	As per COA
Immunoreactivity	≥ 80% (Specific binding assay)
Endotoxin	< 10 EU/mg
Sterility (if supplied sterile)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.