Description

D-Glucosamine-3,6-Di-o-Sulphatedisodiumsalt is a highly sulfated derivative of glucosamine, a key amino sugar building block. This specific sulfation pattern at the 3 and 6 positions is critical for imparting unique biological activity, particularly in modulating enzymatic interactions and mimicking natural glycosaminoglycan structures. It serves as a valuable high-purity biochemical intermediate and research standard for pharmaceutical development, nutraceutical research, and advanced life science applications.

Application

• Pharmaceutical R&D Intermediate: Used in the synthesis and study of novel heparinoid mimetics and chondroprotective agents.
• Biochemical Research Standard: Acts as a reference compound for studying sulfotransferase enzyme activity, carbohydrate-protein interactions, and glycobiology pathways.
• Nutraceutical Ingredient Precursor: Investigated for the development of advanced joint health supplements with enhanced bioavailability and efficacy.
• Glycosaminoglycan (GAG) Analog Synthesis: A key building block for creating synthetic analogs of heparan sulfate and other sulfated polysaccharides.
• Cell Culture & Biomedical Studies: Employed in research focused on extracellular matrix (ECM) modulation, inflammation, and cartilage tissue engineering.
• Cosmeceutical Actives: Explored for use in high-end skincare formulations targeting skin barrier function and hydration.

Basic Information

Item	Details
Product Name	D-Glucosamine-3,6-Di-o-Sulphatedisodiumsalt
CAS No.	536741-53-4
Molecular Formula	C6H11NO11S2•2Na
Molecular Weight	407.23 g/mol
Synonyms	D-Glucosamine 3,6-Disulfate Disodium Salt; Glucosamine-3,6-Disulfate Sodium Salt; 3,6-Di-O-sulfo-D-glucosamine Disodium Salt; 2-Amino-2-deoxy-3,6-di-O-sulfo-D-glucopyranose Disodium Salt; D-GlcN-3,6-S Disodium; Chondrosulf; Sodium Glucosamine Disulfate
EINECS	Contact for details

Quality Control

Our D-Glucosamine-3,6-Di-o-Sulphatedisodiumsalt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity, identity, and consistency, suitable for demanding research and development purposes. A detailed Certificate of Analysis (COA) providing specifications for assay, purity (by HPLC), residual solvents, and heavy metals is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
pH (5% solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.