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1H-Inden-2-Ol,1-Amino-2,3-Dihydro-7-(1-Methylethyl)-,(1R,2S)-Rel-(9Ci) CAS NO 535969-22-3


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CAS No.:535969-22-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1H-Inden-2-Ol,1-Amino-2,3-Dihydro-7-(1-Methylethyl)-,(1R,2S)-Rel-(9Ci) is a chiral, stereochemically defined amino alcohol derivative of indene, serving as a sophisticated building block in advanced organic synthesis. Its precise stereochemistry and functional groups make it a critical intermediate for constructing complex molecular architectures with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is utilized to develop novel active ingredients and chiral ligands.

Application

  • Pharmaceutical Intermediate: Key chiral synthon for the development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
  • Agrochemical Synthesis: Building block for creating enantiomerically pure pesticides and herbicides with enhanced efficacy and environmental profiles.
  • Catalyst and Ligand Development: Precursor for synthesizing novel chiral ligands used in asymmetric catalysis (e.g., hydrogenation, oxidation reactions).
  • Fine Chemical Production: Intermediate in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
  • Academic and R&D: Valuable reference standard and starting material for methodological studies in synthetic organic chemistry and medicinal chemistry research.
  • Material Science: Potential monomer or precursor for advanced polymeric materials with specific optical or mechanical properties.

Basic Information

Product Name 1H-Inden-2-Ol,1-Amino-2,3-Dihydro-7-(1-Methylethyl)-,(1R,2S)-Rel-(9Ci)
CAS No. 535969-22-3
Molecular Formula C12H17NO
Molecular Weight 191.27 g/mol
Synonyms (1R,2S)-1-Amino-7-isopropyl-2,3-dihydro-1H-inden-2-ol; rel-(1R,2S)-1-Amino-7-(1-methylethyl)-2,3-dihydro-1H-inden-2-ol; 1-Amino-7-isopropyl-2,3-dihydro-1H-inden-2-ol (rel-(1R,2S)-); 7-Isopropyl-1-aminoindan-2-ol; Amino-isopropyl-dihydroindenol; (1R,2S)-7-Isopropyl-1-aminoindan-2-ol (relative); Chiral Amino Indanol Derivative
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Quality Control

Our production of this advanced chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric excess (ee). Quality is verified through comprehensive analytical techniques including chiral HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, chiral purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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