Description

5-Bromo-2-[[[[4-(1,1-Dimethylethyl)Benzoyl]Amino]Thioxomethyl]Amino]-Benzoic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it offers a critical building block for research and development in medicinal chemistry, enabling the creation of novel therapeutic agents. It is primarily needed by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on developing new drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly in oncology and antiviral research.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• Chemical Synthesis: Serves as a specialized building block for constructing complex heterocyclic compounds and functionalized benzoic acid derivatives.
• API Manufacturing: Employed in the pilot-scale and commercial-scale production of target active pharmaceutical ingredients requiring this specific brominated thiourea-benzoic acid scaffold.

Basic Information

Product Name	5-Bromo-2-[[[[4-(1,1-Dimethylethyl)Benzoyl]Amino]Thioxomethyl]Amino]-Benzoic Acid
CAS No.	532416-55-0
Molecular Formula	C20H20BrN3O3S
Molecular Weight	462.36 g/mol
Synonyms	5-Bromo-2-[[(4-tert-butylbenzoyl)carbamothioyl]amino]benzoic acid; 2-[[(4-tert-Butylbenzoyl)carbamothioyl]amino]-5-bromobenzoic acid; 5-Bromo-2-[(4-tert-butylbenzoyl)thioureido]benzoic acid; Benzoic acid, 5-bromo-2-[[[[4-(1,1-dimethylethyl)benzoyl]amino]thioxomethyl]amino]-; 532416-55-0; 5-Bromo-N-[(4-tert-butylbenzoyl)carbamothioyl]anthranilic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-[[[[4-(1,1-Dimethylethyl)Benzoyl]Amino]Thioxomethyl]Amino]-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.