Description

Spiro[2.4]Heptane-5-Carboxylic Acid, 6-(Hydroxymethyl)-, Ethyl Ester, (5R,6R)-Rel- (9Ci) is a high-value, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its unique spirocyclic structure and functional groups make it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in programs targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Used in the creation of novel, stereoselective herbicides, fungicides, or insecticides where the specific spatial orientation of the molecule is critical for bioactivity.
• Ligand and Catalyst Development: Serves as a sophisticated backbone for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers with unique thermal or mechanical properties derived from its rigid spiro structure.
• Academic & Industrial R&D: Employed in methodological chemistry research to explore new synthetic pathways and reaction mechanisms involving strained ring systems.

Basic Information

Product Name	Spiro[2.4]Heptane-5-Carboxylic Acid, 6-(Hydroxymethyl)-, Ethyl Ester, (5R,6R)-Rel- (9Ci)
CAS No.	530105-65-8
Molecular Formula	C11H16O3
Molecular Weight	196.24 g/mol
Synonyms	rel-(5R,6R)-6-(Hydroxymethyl)spiro[2.4]heptane-5-carboxylic acid ethyl ester; Ethyl (5R,6R)-6-(hydroxymethyl)spiro[2.4]heptane-5-carboxylate; (5R,6R)-6-(Hydroxymethyl)spiro[2.4]heptane-5-carboxylic Acid Ethyl Ester; Spiro[2.4]heptane-5-carboxylic acid, 6-(hydroxymethyl)-, ethyl ester, (5R,6R)-rel-; Ethyl 6-(hydroxymethyl)spiro[2.4]heptane-5-carboxylate (rel-(5R,6R)-form)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (rel-(5R,6R)-)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.