Description

1-Bromo-4-(Neopentyloxy)Benzene is a high-purity, specialty aromatic ether building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a bromine substituent and a bulky, branched neopentyloxy group, makes it a valuable precursor for constructing complex molecules where steric and electronic properties are critical. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as ligand synthesis, polymer modification, and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly where the neopentyloxy group influences bioavailability or metabolic stability.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides, leveraging its aromatic bromine for further functionalization.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands used in homogeneous catalysis, including cross-coupling reactions.
• Material Science & Polymer Chemistry: Incorporated into monomers for the production of specialty polymers, liquid crystals, or organic electronic materials to modify thermal and optical properties.
• Chemical Research & Development: Employed in academic and industrial R&D for method development, such as in Suzuki-Miyaura or Buchwald-Hartwig cross-coupling reactions, due to its reactive bromine site.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex dyes, fragrances, and other high-value fine chemicals.

Basic Information

Product Name	1-Bromo-4-(Neopentyloxy)Benzene
CAS No.	528528-58-7
Molecular Formula	C11H15BrO
Molecular Weight	243.14 g/mol
Synonyms	4-Bromophenyl neopentyl ether; p-Bromophenyl neopentyl ether; 1-Bromo-4-(2,2-dimethylpropoxy)benzene; Benzene, 1-bromo-4-(2,2-dimethylpropoxy)-; Neopentyl 4-bromophenyl ether; 4-(Neopentyloxy)bromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(Neopentyloxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support cGMP and ISO guidelines for quality assurance to ensure supply chain reliability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.