Description

n-(3-Chloro-4-Fluorophenyl)-N'-(4,6-Dimethylpyrimidin-2-Yl)Guanidine is a high-purity guanidine derivative featuring a unique halogenated aromatic and substituted pyrimidine structure. This compound is a critical pharmaceutical intermediate and agrochemical building block, valued for its role in synthesizing advanced active ingredients. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Serves as a crucial building block for the manufacture of advanced herbicides, fungicides, and insecticides.
• Chemical Research: Used in academic and industrial laboratories for studying structure-activity relationships (SAR) and developing novel chemical entities.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of active pharmaceutical ingredients (APIs).
• Material Science: Potential precursor for the synthesis of specialized polymers or ligands with specific electronic or binding properties.

Basic Information

Product Name	n-(3-Chloro-4-Fluorophenyl)-N'-(4,6-Dimethylpyrimidin-2-Yl)Guanidine
CAS No.	524057-25-8
Molecular Formula	C13H13ClFN5
Molecular Weight	293.73 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)-3-(4,6-dimethylpyrimidin-2-yl)guanidine; Guanidine, N-(3-chloro-4-fluorophenyl)-N'-(4,6-dimethyl-2-pyrimidinyl)-; 524057-25-8; 3-Chloro-4-fluoro-N'-(4,6-dimethylpyrimidin-2-yl)benzenecarboximidamide; N-(3-Chloro-4-fluorophenyl)-N'-(4,6-dimethylpyrimidin-2-yl)guanidine
EINECS	Contact for details

Quality Control

Our n-(3-Chloro-4-Fluorophenyl)-N'-(4,6-Dimethylpyrimidin-2-Yl)Guanidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.