Description

3-Benzyl-3-Azabicyclo[3.2.1]Octan-8-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique bridged bicyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and analgesic therapeutics. It is primarily utilized by research institutions, custom synthesis organizations, and pharmaceutical manufacturers engaged in innovative drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Custom Synthesis & Contract Manufacturing: A key starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological systems and enzyme functions.

Basic Information

Product Name	3-Benzyl-3-Azabicyclo[3.2.1]Octan-8-Ol
CAS No.	522608-86-2
Molecular Formula	C₁₅H₂₁NO
Molecular Weight	231.33 g/mol
Synonyms	3-Benzyl-3-azabicyclo[3.2.1]octan-8-ol; 8-Hydroxy-3-benzyl-3-azabicyclo[3.2.1]octane; 3-Benzyl-8-hydroxy-3-azabicyclo[3.2.1]octane; Bicyclo[3.2.1]octan-8-ol, 3-(phenylmethyl)-3-aza-; 3-Benzyl-3-aza-bicyclo[3.2.1]octan-8-ol; 522608-86-2; 3-Benzyl-8-hydroxy-3-azabicyclo[3.2.1]octane
EINECS	Contact for details

Quality Control

Our 3-Benzyl-3-Azabicyclo[3.2.1]Octan-8-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.