Description

2-Butanone, 3-Nitro-, (3S)- (9Ci) is a chiral nitro ketone compound, a valuable building block in organic synthesis. Its defined stereochemistry at the 3-position makes it a critical intermediate for the preparation of enantiomerically pure pharmaceuticals and agrochemicals. This high-purity chiral synthon is essential for research and development chemists in the pharmaceutical, fine chemical, and advanced material sectors seeking to introduce stereochemical complexity into target molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological and cardiovascular diseases.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and pesticides where specific stereochemistry is required for bioactivity.
• Asymmetric Catalysis Research: Serves as a standard substrate or ligand precursor in the development and screening of new chiral catalysts and methodologies.
• Fine Chemical Manufacturing: Employed in multi-step syntheses of complex natural products, flavors, and fragrances requiring precise stereocontrol.
• Material Science: Potential monomer or modifying agent for creating chiral polymers and advanced functional materials with specific optical properties.

Basic Information

Product Name	2-Butanone, 3-Nitro-, (3S)- (9Ci)
CAS No.	521087-49-0
Molecular Formula	C4H7NO3
Molecular Weight	117.10 g/mol
Synonyms	(3S)-3-Nitrobutan-2-one; (S)-3-Nitro-2-butanone; L-3-Nitro-2-butanone; 3-Nitro-2-butanone, (S)-; (-)-(S)-3-Nitro-2-butanone; (S)-(-)-3-Nitro-2-butanone; 2-Butanone, 3-nitro-, (3S)-; Chiral 3-nitro-2-butanone
EINECS	Contact for details

Quality Control

Our 2-Butanone, 3-Nitro-, (3S)- (9Ci) is produced under strict quality management systems. Each batch is characterized and tested to ensure high chemical and enantiomeric purity, meeting the stringent requirements of advanced synthetic applications. Comprehensive analytical data, including chiral HPLC/GC for enantiomeric excess (ee) determination, is provided. Certificates of Analysis (COA) with full specification compliance are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material may be light-sensitive and should be handled under an inert atmosphere for long-term storage to maintain purity and chiral integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.