Description

Quinoline, 4-Ethynyl-1,2,3,5,6,7,8,8A-Octahydro-2-Methyl-, (2R,8As)-Rel- (9Ci) is a specialized, high-purity chemical intermediate characterized by its complex, partially saturated quinoline core and an ethynyl functional group. This compound matters for its role as a sophisticated building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders or infectious diseases.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the quinoline scaffold can contribute to biological activity.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing novel ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced organic electronic materials or polymers.
• Academic & Contract Research: Employed in university laboratories and CROs (Contract Research Organizations) for methodological studies and the exploration of new chemical reactions.
• Fine Chemical Synthesis: Utilized in multi-step synthetic routes to produce other high-value, complex specialty chemicals.

Basic Information

Product Name	Quinoline, 4-Ethynyl-1,2,3,5,6,7,8,8A-Octahydro-2-Methyl-, (2R,8As)-Rel- (9Ci)
CAS No.	519164-95-5
Molecular Formula	C12H15N
Molecular Weight	173.25 g/mol
Synonyms	(2R,8aS)-4-Ethynyl-2-methyl-1,2,3,5,6,7,8,8a-octahydroquinoline; rel-(2R,8aS)-4-Ethynyl-2-methyl-1,2,3,4,5,6,7,8-octahydroquinoline; 4-Ethynyl-2-methyl-1,2,3,4,5,6,7,8-octahydroquinoline; 4-Ethynyl-2-methyl-decahydroquinoline (relative stereochemistry); Octahydro-4-ethynyl-2-methylquinoline; CAS 519164-95-5
EINECS	Contact for details

Quality Control

Our production of Quinoline, 4-Ethynyl-1,2,3,5,6,7,8,8A-Octahydro-2-Methyl-, (2R,8As)-Rel- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing specific results for purity, enantiomeric excess, and impurity profiles are provided with every shipment. We support development and scale-up projects with reliable, research-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and ensure long-term stability. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.