Description

6-(4-Fluoro-Phenylsulfamoyl)-2-Hydroxy-Quinoline-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex quinoline-carboxylic acid structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, particularly in areas requiring sophisticated sulfonamide and fluorinated building blocks.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly for anti-infective or anti-inflammatory applications.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• API Synthesis: Used in the multi-step production of complex Active Pharmaceutical Ingredients (APIs) that incorporate quinoline and sulfonamide pharmacophores.
• Biochemical Research: Potential use as a tool compound or inhibitor in biochemical assays and target validation studies.
• Reference Standard: Suitable for use as an analytical reference standard in quality control laboratories for method development and validation.

Basic Information

Item	Details
Product Name	6-(4-Fluoro-Phenylsulfamoyl)-2-Hydroxy-Quinoline-4-Carboxylic Acid
CAS No.	519152-68-2
Molecular Formula	C₁₇H₁₁FN₂O₅S
Molecular Weight	374.35 g/mol
Synonyms	6-[(4-Fluorophenyl)sulfamoyl]-2-hydroxyquinoline-4-carboxylic acid; 2-Hydroxy-6-[(4-fluorophenyl)sulfamoyl]-4-quinolinecarboxylic acid; 6-(4-Fluorophenylsulfamoyl)-2-hydroxyquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 6-[(4-fluorophenyl)sulfamoyl]-2-hydroxy-; 519152-68-2; FPHQC; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 6-(4-Fluoro-Phenylsulfamoyl)-2-Hydroxy-Quinoline-4-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.