Description

2-Ethyl-1,2,3,4-Tetrahydro-Benzo[B][1,6]Naphthyridine-10-Carboxylic Acid is a complex heterocyclic carboxylic acid derivative that serves as a critical advanced intermediate in modern organic synthesis. Its value lies in its fused polycyclic structure, which provides a versatile scaffold for constructing pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new bioactive chemical space.
• Process Chemistry Development: Serves as a critical intermediate in scaling up and optimizing synthetic routes for potential active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	2-Ethyl-1,2,3,4-Tetrahydro-Benzo[B][1,6]Naphthyridine-10-Carboxylic Acid
CAS No.	519150-65-3
Molecular Formula	C15H16N2O2
Molecular Weight	256.30 g/mol
Synonyms	2-Ethyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine-10-carboxylic acid; 10-Carboxy-2-ethyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine; 2-Ethyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine-10-carboxylic acid; Benzo[b][1,6]naphthyridine-10-carboxylic acid, 2-ethyl-1,2,3,4-tetrahydro-; 519150-65-3; 2-Ethyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine-10-carboxylate (deprotonated form)
EINECS	Contact for details

Quality Control

Our 2-Ethyl-1,2,3,4-Tetrahydro-Benzo[B][1,6]Naphthyridine-10-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.