Description

C-(4'-Fluoro-Biphenyl-4-Yl)-Methylamine Hydrochloride is a high-purity, synthetically derived organic salt primarily used as a critical pharmaceutical intermediate. This compound is valued for its role in the synthesis of advanced active pharmaceutical ingredients (APIs) and other fine chemicals, where structural precision is paramount. It is essential for research and development chemists, process scale-up teams, and manufacturers in the pharmaceutical and agrochemical sectors seeking reliable building blocks for complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides that require specific biphenyl-based structures.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated biphenyl components for electronic display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the research and manufacture of electron-transport or host materials for OLED devices.
• Academic & Contract Research: Utilized in universities and CROs for methodological development and structure-activity relationship (SAR) studies.
• Custom Synthesis & Scaling: A starting material for contract manufacturing organizations (CMOs) performing custom synthesis and process optimization.

Basic Information

Product Name	C-(4'-Fluoro-Biphenyl-4-Yl)-Methylamine Hydrochloride
CAS No.	518357-40-9
Molecular Formula	C14H13ClFN
Molecular Weight	249.71 g/mol
Synonyms	1-[(4'-Fluoro[1,1'-biphenyl]-4-yl)methyl]methanamine hydrochloride; (4'-Fluoro-biphenyl-4-ylmethyl)-methyl-amine hydrochloride; 4'-(Aminomethyl)-4-fluorobiphenyl hydrochloride; N-Methyl-1-(4'-fluorobiphenyl-4-yl)methanamine hydrochloride; 1-[(4'-Fluoro-4-biphenylyl)methyl]methylamine hydrochloride; 4-(Aminomethyl)-4'-fluorobiphenyl hydrochloride; [4-(4-Fluorophenyl)phenyl]methyl(methyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our C-(4'-Fluoro-Biphenyl-4-Yl)-Methylamine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting compliance in GMP-aligned applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Ensure adequate ventilation in the storage area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.