Description

Cyclopropanecarboxaldehyde, 2,2,3-Trimethyl-3-Nitro-, (1R,3S)- (9Ci) is a high-purity, chiral nitrocyclopropane derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and stereochemically defined building block for constructing complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. The specific stereochemistry (1R,3S) makes it a valuable intermediate for creating enantiomerically pure target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in programs targeting small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel, stereoselective pesticides and herbicides where the specific spatial arrangement of the molecule influences biological activity.
• Methodology Development: Serves as a model substrate in academic and industrial research for developing new asymmetric synthesis and cyclopropanation reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Ligand and Catalyst Precursor: Can be utilized to synthesize novel chiral ligands or organocatalysts for asymmetric catalysis.

Basic Information

Product Name	Cyclopropanecarboxaldehyde, 2,2,3-Trimethyl-3-Nitro-, (1R,3S)- (9Ci)
CAS No.	518352-35-7
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	(1R,3S)-2,2,3-Trimethyl-3-nitrocyclopropanecarboxaldehyde; (1R,3S)-2,2,3-Trimethyl-3-nitrocyclopropanecarbaldehyde; (1R,3S)-3-Nitro-2,2,3-trimethylcyclopropanecarboxaldehyde; 2,2,3-Trimethyl-3-nitrocyclopropanecarboxaldehyde, (1R,3S)-; (1R,3S)-rel-2,2,3-Trimethyl-3-nitrocyclopropanecarboxaldehyde; Nitrocyclopropane carboxaldehyde derivative
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxaldehyde, 2,2,3-Trimethyl-3-Nitro-, (1R,3S)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. All materials are characterized by modern analytical techniques including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.