Description

Exo-3-(4-Methylbenzoyl)-Bicyclo[2.2.1]Heptane-Endo-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique bicyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities, offering a versatile chiral building block for medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in the areas of central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates.
• Medicinal Chemistry Research: Used as a sophisticated building block for constructing complex molecular architectures in drug discovery programs.
• API Synthesis: Serves as a precursor in the multi-step synthesis of target active pharmaceutical ingredients.
• Asymmetric Synthesis: Leveraged for its defined stereochemistry in creating enantiomerically pure compounds.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic & Industrial R&D: Utilized in exploratory chemistry for developing new synthetic methodologies and novel compounds.

Basic Information

Product Name	Exo-3-(4-Methylbenzoyl)-Bicyclo[2.2.1]Heptane-Endo-2-Carboxylic Acid
CAS No.	517892-17-0
Molecular Formula	C16H18O3
Molecular Weight	258.31 g/mol
Synonyms	3-(4-Methylbenzoyl)bicyclo[2.2.1]heptane-2-carboxylic acid (endo,exo-mixture); Bicyclo[2.2.1]heptane-2-carboxylic acid, 3-(4-methylbenzoyl)-, endo,exo-; 3-(p-Toluoyl)bicyclo[2.2.1]heptane-2-carboxylic acid; 3-(4-Methylbenzoyl)-2-norbornanecarboxylic acid; endo,exo-3-(4-Methylbenzoyl)-2-norbornanecarboxylic acid; 517892-17-0; 3-(4-Methylbenzoyl)norbornane-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our Exo-3-(4-Methylbenzoyl)-Bicyclo[2.2.1]Heptane-Endo-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Exo/Endo as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.