Description

Quinoline, 2-Ethyl-4-(Trifluoromethyl)- (9Ci) is a specialized fluorinated quinoline derivative, a high-value building block prized for its unique combination of a heterocyclic core and a trifluoromethyl group. This compound is critical for introducing lipophilicity and metabolic stability into advanced molecular architectures. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-infectives, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing organic electronic materials, such as ligands for OLEDs or charge-transport materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic processes, including cross-coupling reactions.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on the synthesis and reactivity of fluorinated heterocycles.

Basic Information

Product Name	Quinoline, 2-Ethyl-4-(trifluoromethyl)- (9Ci)
CAS No.	515845-47-3
Molecular Formula	C12H10F3N
Molecular Weight	225.21 g/mol
Synonyms	2-Ethyl-4-(trifluoromethyl)quinoline; 4-(Trifluoromethyl)-2-ethylquinoline; 2-Ethyl-4-trifluoromethylquinoline; Quinoline, 2-ethyl-4-(trifluoromethyl)-; 515845-47-3
EINECS	Contact for details

Quality Control

Our production of 2-Ethyl-4-(trifluoromethyl)quinoline adheres to stringent quality management protocols. Every batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for research and scale-up activities. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), physical data, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is sensitive to strong alkali and fluorides; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	Contact for details
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.