Description

Quinoline, 4-Ethyl-2-(Trifluoromethyl)- (9Ci) is a specialized fluorinated quinoline derivative, a high-value building block prized for its unique trifluoromethyl and ethyl substituents which impart significant electronic and steric properties. This compound is essential for advanced research and development in medicinal chemistry and materials science, where its structural motifs are leveraged to modulate biological activity and material characteristics. It is primarily sought by pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the synthesis of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials or host materials in OLED devices due to its robust quinoline core and fluorine content.
• Ligand Synthesis in Catalysis: Employed to create sophisticated nitrogen-containing ligands for transition metal catalysts used in cross-coupling and other organic transformations.
• Fluorescent Probe Development: Utilized as a core structure for designing fluorescent dyes and sensors for biological imaging and diagnostic applications.
• Academic & Industrial R&D: A valuable reference standard and starting material for exploratory chemistry in universities and corporate R&D laboratories.

Basic Information

Product Name	Quinoline, 4-Ethyl-2-(Trifluoromethyl)- (9Ci)
CAS No.	515845-46-2
Molecular Formula	C12H10F3N
Molecular Weight	225.21 g/mol
Synonyms	4-Ethyl-2-(trifluoromethyl)quinoline; 2-(Trifluoromethyl)-4-ethylquinoline; 4-Ethyl-2-trifluoromethylquinoline; Quinoline, 4-ethyl-2-(trifluoromethyl)-; 515845-46-2; 4-Ethyl-2-trifluoromethyl-quinoline; 4-Ethyl-2-(trifluoromethyl)quinoline (9CI)
EINECS	Contact for details

Quality Control

Every batch of 4-Ethyl-2-(Trifluoromethyl)quinoline is produced and analyzed under strict quality management protocols to ensure consistency and high purity for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.