Description

8-Amino-3-Bromo-6-Fluoroquinoline is a high-purity, multi-functional quinoline derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and aminated structure makes it a versatile intermediate for constructing complex molecular architectures with tailored properties. This compound is essential for research and development in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel fluoroquinolone antibiotics and other bioactive molecules targeting bacterial infections.
• Agrochemical Synthesis: Building block for developing next-generation fungicides and herbicides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of organic semiconductors, fluorescent dyes, and metal-chelating ligands due to its electron-rich quinoline core.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and inhibitors for studying enzyme mechanisms and cellular processes.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific halogen and amine functionalization on a quinoline backbone.

Basic Information

Product Name	8-Amino-3-Bromo-6-Fluoroquinoline
CAS No.	515170-53-3
Molecular Formula	C9H6BrFN2
Molecular Weight	241.06 g/mol
Synonyms	3-Bromo-6-fluoro-8-aminoquinoline; 6-Fluoro-8-amino-3-bromoquinoline; 8-Amino-6-fluoro-3-bromoquinoline; Quinoline, 8-amino-3-bromo-6-fluoro-; 515170-53-3; 3-Bromo-6-fluoroquinolin-8-amine
EINECS	Contact for details

Quality Control

Our 8-Amino-3-Bromo-6-Fluoroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.