Description

3-Bromo-6-Fluoro-8-Nitro-Quinoline is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique halogenated and nitrated quinoline structure makes it a critical intermediate for constructing complex molecules with tailored electronic and biological properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antimicrobials, and other therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated quinoline core for bioactivity.
• Material Science: Acts as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromo and nitro groups, enabling diverse functionalization.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized quinoline-based dyes and colorants.
• Academic & Contract Research: A valuable reagent for universities and CROs conducting fundamental research in heterocyclic and organofluorine chemistry.

Basic Information

Product Name	3-Bromo-6-Fluoro-8-Nitro-Quinoline
CAS No.	515170-51-1
Molecular Formula	C9H4BrFN2O2
Molecular Weight	271.04 g/mol
Synonyms	8-Nitro-3-bromo-6-fluoroquinoline; 6-Fluoro-3-bromo-8-nitroquinoline; 3-Bromo-6-fluoro-8-nitroquinoline; Quinoline, 3-bromo-6-fluoro-8-nitro-; 515170-51-1; 3-Br-6-F-8-NO2-Quinoline
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-6-Fluoro-8-Nitro-Quinoline is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and MS to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.