Description

n-(tert-Butyl)-3-Iodo-4-Methylbenzamide CAS NO 514794-68-4 is a high-purity, halogenated benzamide derivative serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the sterically hindered tert-butyl amide group and the reactive iodine substituent, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or requiring sophisticated amide linkages.
• Agrochemical Research: Used in creating novel herbicides, fungicides, or insecticides where the iodine atom facilitates further functionalization for bioactivity optimization.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science: Building block for advanced organic materials, such as liquid crystals or polymers with specific electronic properties.
• Chemical Biology Probes: Utilized in creating molecular probes for studying biological processes due to the reactivity of the iodine handle for bioconjugation.
• Custom Synthesis & Scale-up: Supplied for contract research organizations (CROs) and development companies requiring reliable, high-quality advanced intermediates.

Basic Information

Product Name	n-(tert-Butyl)-3-Iodo-4-Methylbenzamide
CAS No.	514794-68-4
Molecular Formula	C12H16INO
Molecular Weight	317.17 g/mol
Synonyms	3-Iodo-N-(tert-butyl)-4-methylbenzamide; N-tert-Butyl-3-iodo-p-toluamide; 4-Methyl-3-iodo-N-(1,1-dimethylethyl)benzamide; 3-Iodo-4-methyl-N-(2-methyl-2-propanyl)benzamide; Benzamide, 3-iodo-N-(1,1-dimethylethyl)-4-methyl-; N-(tert-Butyl)-3-iodo-4-methylbenzamide; tert-Butyl 3-iodo-4-methylbenzamide
EINECS	Contact for details

Quality Control

Our n-(tert-Butyl)-3-Iodo-4-Methylbenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.