Description

2-(2,4-Difluoro-Phenyl)-Quinoline is a high-purity, fluorinated quinoline derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in its unique molecular structure, which serves as a versatile building block for constructing complex molecules with tailored properties. This compound is primarily needed by research institutions and industrial R&D teams in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used as a core structural component in the synthesis of next-generation pesticides and herbicides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for organic light-emitting diodes (OLEDs) and other electronic materials due to the quinoline scaffold's electron-transport properties.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for transition metal catalysis, facilitating challenging chemical transformations.
• Fluorescent Probe Synthesis: Utilized in the design and synthesis of fluorescent markers and sensors for biochemical and diagnostic applications.
• Academic & Industrial R&D: A fundamental research chemical for exploring new synthetic methodologies and structure-activity relationships (SAR) in various chemical disciplines.

Basic Information

Product Name	2-(2,4-Difluoro-Phenyl)-Quinoline
CAS No.	512180-22-2
Molecular Formula	C15H9F2N
Molecular Weight	241.24 g/mol
Synonyms	2-(2,4-Difluorophenyl)quinoline; Quinoline, 2-(2,4-difluorophenyl)-; 2-(2,4-Difluorophenyl)chinolin; 2-(2,4-Difluorophenyl)quinoleine; 2-(2,4-Difluorophenyl)-quinolin; 2-(2,4-Difluoro-phenyl)-chinolin; 512180-22-2
EINECS	Contact for details

Quality Control

Our 2-(2,4-Difluoro-Phenyl)-Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our commitment to quality supports your R&D and scale-up processes with reliable, high-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.