Description

2-[3-(Trifluoromethyl)Isoxazol-5-Yl]Phenol is a high-value fluorinated heterocyclic building block featuring a phenol group attached to a trifluoromethyl-substituted isoxazole ring. This unique molecular architecture makes it a critical intermediate for synthesizing advanced agrochemicals and pharmaceuticals, where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily sought by R&D chemists and process development scientists in the fine chemical, crop protection, and pharmaceutical industries for creating novel active ingredients.

Application

• Agrochemical Intermediate: A key synthon for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl and isoxazole motifs.
• Pharmaceutical Building Block: Used in medicinal chemistry for the synthesis of potential drug candidates targeting various diseases, where the phenol group allows for further functionalization.
• Material Science Research: Serves as a precursor for specialty polymers or liquid crystals, exploring the incorporation of fluorinated heterocycles to modify material properties.
• Chemical Synthesis Reagent: Employed in organic synthesis as a versatile scaffold for constructing more complex fluorinated molecules through coupling and derivatization reactions.

Basic Information

Product Name	2-[3-(Trifluoromethyl)Isoxazol-5-Yl]Phenol
CAS No.	511528-92-0
Molecular Formula	C10H6F3NO2
Molecular Weight	229.16 g/mol
Synonyms	5-(2-Hydroxyphenyl)-3-(trifluoromethyl)-1,2-oxazole; 2-[3-(Trifluoromethyl)-1,2-oxazol-5-yl]phenol; Phenol, 2-[3-(trifluoromethyl)-5-isoxazolyl]-; 3-Trifluoromethyl-5-(2-hydroxyphenyl)isoxazole
EINECS	Contact for details

Quality Control

Our production of 2-[3-(Trifluoromethyl)Isoxazol-5-Yl]Phenol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, IR) to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.